WHAT DOES IS NEMBUTAL LEGAL IN USA MEAN?

Check Closely (1)pentobarbital will lower the level or impact of fentanyl by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Intently. Coadministration of fentanyl with CYP3A4 inducers could lead to some decrease in fentanyl plasma concentrations, insufficient efficacy or, possibly, advancement of a withdrawal syndrome